| Customization: | Available |
|---|---|
| CAS No.: | Yes |
| Formula: | Yes |
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| Item | Specifications |
| Appearance | White powder. |
| Purity | 99%min |
| Vapor Pressure | 0.0±0.6 mmHg at 25ºC |
| LogP | -2.02 |
| Boiling point | 959.8±65.0ºC at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Refractive index | 1.559 |
| Flash point | 534.3±34.3ºC |
| Storage condition | -20ºC |
| Shelf life | 2 years |
Application:
Humanin is a micro-peptide, which means it is produced by short, open reading frames and does not undergo modification once
produced. According to studies, this type of peptide ranges in size from 100-150 amino acids in length.
At only 24 amino acids in length, Humanin is actually one of the smallest micropeptides available. Its main feature is its interaction
with the Bax protein to regulate apoptosis, eliminating the function of it when needed to preserve cells.
Humanin (HN) is a polypeptide and a naturally occurring micro-peptide which suppresses neuronal cell death induced by various
Alzheimer's disease genes as studies showed. The Humanin peptide is encoded in the mitochondrial DNA[i] and functions as
acytoprotective protein, protecting cells from apoptosis. Apoptosis is programmed cell death. By protecting the cells from this lethal
process, it keeps the cells healthy and protects neurons, muscle cells, cardiac tissue, and the retina of the eye as tests showed.
Research shows that humanin treatment can improve cardiovascular disease and Alzheimer's disease. With more extensive
research, it could soon become an available over-the-counter medication for such health conditions.
Product Benefits:
Humanin is an endogenous mitochondria-derived peptide that has cytoprotective effects and reduces oxidative stress.
Experiments using cultured cells have demonstrated that humanin has both neuroprotective as well as cytoprotective effects and
experiments in rodents have found that it has protective effects in Alzheimer's disease models, Huntington's disease models and
stroke models. Humanin is proposed to have myriad neuroprotective and cytoprotective effects.
Both studies in cells and rodents have both found that administration of humanin or humanin derivatives increases survival and/or
physiological parameters in Alzheimer's disease models.
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